Related Experiment Video
Updated: May 16, 2026
10:31
Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
Published on: August 9, 2016
Prognostic factors in gastric carcinoma after R0 resection with DII lymph node dissection. Tunisian experience
Sofiene Ayadi1, Amine Daghfous, Amine Makni
1Department of General Surgery, Rabta Hospital, Tunis, Tunisia.
La Tunisie Medicale
|December 1, 2012
Summary
For gastric cancer patients undergoing R0 resection and DII lymph node dissection, tumor invasion depth, lymph node status, and retrieving over 15 lymph nodes are key survival predictors.
Area of Science:
- Surgical Oncology
- Gastrointestinal Surgery
- Cancer Research
Background:
- Curative resection with adequate lymph node dissection is the standard treatment for gastric cancer.
- Optimizing surgical outcomes requires understanding prognostic factors post-resection.
Purpose of the Study:
- To identify independent prognostic factors influencing survival after R0 resection and DII lymph node dissection for gastric cancer.
Main Methods:
- Retrospective analysis of 126 gastric cancer patients (excluding upper third) undergoing R0 resection with DII lymphadenectomy (1991-2006).
- Cox proportional hazard model used to assess prognostic factors.
- Median follow-up of 38.5 months.
Main Results:
- 50% of tumors were stage T3; median 11 lymph nodes removed, with 50% positive for metastasis.
- Five- and 10-year survival rates were 56.9% and 40.2%, respectively.
- Multivariable analysis identified depth of wall invasion, lymph node involvement, and retrieval of >15 lymph nodes as independent prognostic factors.
Conclusions:
- Depth of gastric cancer invasion, lymph node metastasis, and the number of retrieved lymph nodes (>15) are critical independent predictors of survival.
- These factors are crucial for patient stratification and prognosis after curative resection with DII lymphadenectomy.
