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Updated: May 16, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
[Primary malignant tumors of the sternum]
Alia Zehani1, Aida Ayadi-Kaddour, Adel Marghli
1Hopital Abderrahman Mami-Ariana, Tunisie.
Background:
Primary tumors of the sternum are rare and account only 0.5% of all primary bone tumors. They are often malignant, osteolytic and aggressive. They often present difficulties in management.
Aim:
to determine clinical, pathological and therapeutic characteristics for primary malignant tumors of the sternum.
Patients And Methods:
We report a series of six cases of primary malignant tumors of the sternum, collected in our institution between 1993 and 2009.
Results:
There were 4 men and 2 women with a mean age of 69, 5 years. Parietal swelling was the most frequent symptom. Imaging showed a sternal lytic lesion. Three tumors were treated surgically. Associated treatments were neoadjuvant chemotherapy (1 case) and postoperative radiotherapy (1 case). A medical treatment (radiotherapy alone or chemotherapy) was performed in 3 cases. These tumors were divided as below: 3 plasmacytoma, 1 chondrosarcoma, 1 osteosarcoma and 1 large B cell lymphoma.
Conclusion:
The management of primary malignant tumors of the sternum is multidisciplinary. It depends on the histological type, the possibility of surgical treatment and the distant and local aggressiveness.
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