Related Experiment Video
Updated: May 16, 2026
10:33
Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
Psoriasis and uveitis: a literature review
Naiara Abreu de Azevedo Fraga1, Maria de Fátima Paim de Oliveira, Ivonise Follador
1Federal University of Bahia (UFBA) - Salvador (BA), Brazil. naiarafraga@yahoo.com.br
Anais Brasileiros De Dermatologia
|December 1, 2012
Summary
Psoriasis patients, especially those with psoriatic arthritis or pustular psoriasis, have a higher risk of developing uveitis. Regular eye exams are crucial for early detection and treatment to prevent vision loss.
Area of Science:
- Immunology
- Ophthalmology
- Dermatology
Background:
- Psoriasis is a chronic, immune-mediated disease affecting 1-3% of the global population.
- Comorbidities, including metabolic syndrome, are increasingly recognized in psoriasis patients.
- Uveitis is intraocular inflammation with diverse etiologies.
Purpose of the Study:
- To investigate the association between psoriasis, psoriatic arthritis, and uveitis.
- To determine if psoriasis without joint involvement is a risk factor for uveitis.
- To identify specific psoriasis subtypes linked to higher uveitis incidence.
Main Methods:
- Retrospective analysis of patient data.
- Comparison of uveitis incidence in patients with psoriasis versus psoriatic arthritis.
- Subgroup analysis based on psoriasis type (e.g., pustular psoriasis).
Main Results:
- Psoriasis alone, without joint involvement, does not appear to increase uveitis risk.
- Uveitis is more common in patients with psoriatic arthritis or pustular psoriasis.
- Specific subtypes of psoriasis show a stronger association with uveitis development.
Conclusions:
- Psoriatic arthritis and pustular psoriasis are associated with a higher risk of uveitis.
- Ophthalmic surveillance is recommended for patients with psoriasis, particularly those with joint involvement or pustular disease.
- Prompt treatment of associated ophthalmopathy is essential to prevent vision impairment.
Related Concept Videos
01:26Nephrotic Syndrome II : Assessment and Medical Management
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
01:20Asthma: Pathogenesis and Management
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
01:26Inflammatory Bowel Disease I: Introduction
Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
01:24Nephrotic Syndrome I : Introduction
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
01:20Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...