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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: May 16, 2026

Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery

Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery

Published on: September 5, 2018

Improved hepatic arterial phase MRI with 3-second temporal resolution.

Mukta D Agrawal¹, Pascal Spincemaille, Kevin W Mennitt

¹Department of Radiology, Weill Cornell Medical College of Cornell University, New York, New York, USA. map2008@med.cornell.edu

Journal of Magnetic Resonance Imaging : JMRI

|December 1, 2012

Summary

Achieving 3-second temporal resolution in dynamic liver MRI significantly improves arterial phase bolus timing and image quality. This enhanced temporal resolution aids in better visualization of hepatic arteries and overall diagnostic accuracy in liver imaging.

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Phase Contrast Magnetic Resonance Imaging in the Rat Common Carotid Artery

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Area of Science:

Radiology
Medical Imaging
Hepatobiliary Imaging

Background:

Dynamic liver MRI is crucial for diagnosing liver lesions.
Optimal arterial phase timing is essential for accurate dynamic liver MRI interpretation.
Standard Cartesian k-space LAVA (Liver Acquisition with Volume Acceleration) has limitations in achieving rapid temporal resolution.

Purpose of the Study:

To evaluate the effectiveness of 3-second temporal resolution for arterial phase bolus timing in dynamic liver MRI.
To compare the performance of standard Cartesian LAVA with spiral LAVA reconstructed at 3-second temporal resolution.

Main Methods:

A comparative study involving 100 patients with standard Cartesian LAVA and 61 patients with spiral LAVA.
Both groups underwent gadoxetate-enhanced dynamic liver MRI.
Qualitative (bolus timing, vessel visualization, image quality) and quantitative (contrast-to-noise ratios, signal intensity ratios) analyses were performed.

Main Results:

Spiral LAVA achieved optimal arterial phase timing in 88% of patients, compared to 35% with standard LAVA (P < 0.0001).
Spiral LAVA demonstrated superior bolus timing scores, image quality, and hepatic artery visualization.
Quantitative analysis showed a significantly higher aorta to liver parenchyma signal intensity ratio with spiral LAVA (2.8 vs. 2.2; P < 0.001).

Conclusions:

Dynamic liver MRI benefits from 3-second temporal resolution, leading to improved bolus timing.
Spiral k-space LAVA reconstruction at 3-second temporal resolution offers significant advantages over standard Cartesian LAVA for dynamic liver MRI.