Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neonatal aortic stenosis.

K Turley1, E L Bove, J J Amato

  • 1Department of Cardiothoracic Surgery, University of California, San Francisco 94143-0118.

The Journal of Thoracic and Cardiovascular Surgery
|April 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Male factor infertility and placental pathology in singleton live births conceived with in vitro fertilization.

Journal of assisted reproduction and genetics·2021
Same author

Contemporary endovascular management of splenic vascular pathologies.

Clinical radiology·2020
Same author

Serum uric acid does not predict incident metabolic syndrome in a population with high prevalence of obesity.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2014
Same author

P2X7 purinoceptors contribute to the death of Schwann cells transplanted into the spinal cord.

Cell death & disease·2013
Same author

Ferret lung transplant: an orthotopic model of obliterative bronchiolitis.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2012
Same author

Squamous cell carcinoma of the rectum: a single institution experience.

Techniques in coloproctology·2012
Same journal

Undersized Fontan conduits are not without risk.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Predicting high-risk recipients or high-risk donation after circulatory death hearts?

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Outcomes of donation after circulatory death heart transplantation in recipients with pulmonary hypertension.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Reply: Pregnancy-related type A aortic dissection: Expand raw data or refine statistical methodology?

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Extending the age cutoff: Outcomes of the Ross procedure in patients older than 60 years. A two-center retrospective study from the Canadian Ross Registry.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

From High-Risk Fetal Heart Disease to Personalized Life-Long Management: Equity, Globalization and Regionalization in the Era of Artificial Intelligence.

The Journal of thoracic and cardiovascular surgery·2026
See all related articles

Surgical relief of neonatal aortic stenosis using cardiopulmonary bypass stabilization offers high survival rates. This approach, involving open valvotomy or transventricular dilatation, provides a benchmark for comparing newer percutaneous therapies.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Surgery
  • Neonatal Critical Care

Background:

  • Neonatal aortic stenosis historically had high operative mortality.
  • Percutaneous balloon dilatation is a current therapy, but optimal treatment remains debated.

Purpose of the Study:

  • To present results of operative therapy for isolated aortic stenosis in neonates using cardiopulmonary bypass stabilization.
  • To establish a standard for comparison with percutaneous dilatation methods.

Main Methods:

  • Retrospective analysis of 40 neonates (1983-1989) with isolated aortic stenosis and associated conditions.
  • Surgical intervention included open valvotomy (30 patients) and transventricular dilatation (10 patients).
  • All patients received cardiopulmonary bypass for stabilization.

Related Experiment Videos

Main Results:

  • Hospital survival rate was 87.5% (35/40).
  • No significant difference in survival between open valvotomy and transventricular dilatation.
  • High survival rates were consistent across three institutions and various bypass/valvotomy techniques.

Conclusions:

  • Cardiopulmonary bypass stabilization enables high operative and late survival rates for neonatal aortic stenosis.
  • This surgical approach serves as a critical benchmark for evaluating percutaneous dilatation therapies.