Related Experiment Video
Updated: May 16, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Pseudomonas necrotizing fasciitis in an otherwise healthy infant
Shakeel Ahmed1, Syed Rehan Ali, Zahra Aziz Samani
1Department of Paediatrics and Child Health, Aga Khan University Hospital, Stadium Road, P.O. Box 3500, Krachi 74800, Pakistan.
Abstract:
Necrotizing fasciitis is an uncommon rapidly progressing infection of soft tissue characterized by a severe inflammation of the fascia and soft tissue. The disease is associated with necrosis and subcutaneous gangrene of the inflamed tissue with systemic toxicity that carries a significant mortality unless timely diagnosed and aggressively treated. Monomicrobial necrotizing fasciitis caused by Pseudomonas aeruginosa is an exceptionally uncommon condition with only few cases reported in the literature so far. We are reporting a six-month-old female infant who was previously healthy and who presented with necrotizing fasciitis and isolates Pseudomonas aeruginosa both from the blood and tissue. The child improved after the intensive treatment.
Insights
Necrotizing fasciitis, a severe soft tissue infection, is rarely caused by a single bacterium. This case report details a rare instance of monomicrobial necrotizing fasciitis in an infant due to Pseudomonas aeruginosa.
Area of Science:
- Infectious Diseases
- Pediatric Surgery
- Microbiology
Background:
- Necrotizing fasciitis is a rapidly progressive soft tissue infection with high mortality.
- Monomicrobial necrotizing fasciitis is exceptionally rare, with few documented cases.
- Pseudomonas aeruginosa is an opportunistic pathogen not commonly associated with this condition.
Purpose of the Study:
- To report a rare case of monomicrobial necrotizing fasciitis caused by Pseudomonas aeruginosa in an infant.
- To highlight the diagnostic and treatment challenges of this uncommon infection in a pediatric patient.
Main Methods:
- Case report of a six-month-old female infant.
- Clinical presentation, diagnosis, and treatment of necrotizing fasciitis.
- Microbiological analysis of blood and tissue samples for Pseudomonas aeruginosa.
Main Results:
- The infant presented with necrotizing fasciitis.
- Pseudomonas aeruginosa was isolated from both blood and tissue samples.
- The patient improved following intensive treatment.
Conclusions:
- Monomicrobial necrotizing fasciitis due to Pseudomonas aeruginosa can occur in previously healthy infants.
- Early diagnosis and aggressive treatment are crucial for favorable outcomes.
- This case expands the understanding of rare etiologies of necrotizing fasciitis in pediatrics.
Related Concept Videos
Bacterial Meningitis I: Introduction
Staphylococcal Skin Infections
Acute Pyelonephritis I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction
Atypical Pneumonia