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Sinusitis: a rare cause for galactorrhoea.

W O Bennett1, J R Kennedy, V M Reddy

  • 1Department of Otolaryngology-Head and Neck Surgery, Torbay Hospital, South Devon Healthcare NHS Foundation Trust, Torquay TQ2 7AA, UK.

Case Reports in Otolaryngology
|December 1, 2012
PubMed
Summary
This summary is machine-generated.

A rare case of sinusitis causing elevated prolactin (hyperprolactinemia) and galactorrhea is presented. Surgical drainage of a sphenoid sinus mucocele resolved the patient's symptoms, highlighting an unusual link between sinusitis and hormonal imbalance.

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Area of Science:

  • Endocrinology
  • Otolaryngology
  • Radiology

Background:

  • Hyperprolactinemia, characterized by elevated prolactin levels, can cause symptoms like galactorrhea.
  • Pituitary adenomas are the most common cause of hyperprolactinemia.
  • Extrapituitary causes of hyperprolactinemia are rare but important to consider.

Purpose of the Study:

  • To report a case of hyperprolactinemia and galactorrhea secondary to sphenoid sinusitis.
  • To discuss the potential mechanisms linking sinusitis to hyperprolactinemia.
  • To highlight the importance of considering non-pituitary causes for elevated prolactin levels.

Main Methods:

  • A 32-year-old woman presented with galactorrhea and was found to have hyperprolactinemia.
  • Magnetic resonance imaging (MRI) revealed a sphenoid sinus mucocele without pituitary abnormalities.
  • The patient underwent endoscopic sinus surgery to drain the mucocele.

Main Results:

  • Post-surgical drainage of the sphenoid mucocele led to the resolution of galactorrhea and normalization of prolactin levels.
  • The case suggests a potential causal link between sphenoid sinusitis/mucocele and hyperprolactinemia.
  • Literature review identified only one prior case of sinusitis-induced hyperprolactinemia.

Conclusions:

  • Sphenoid sinusitis, particularly when complicated by a mucocele, can be an unusual cause of hyperprolactinemia and galactorrhea.
  • Endoscopic sinus surgery is an effective treatment for resolving symptoms in such cases.
  • This case underscores the need for a comprehensive differential diagnosis in patients presenting with hyperprolactinemia.