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Bilateral Knee Pain Associated with Bone Infarction in a Patient with Behcet's Disease

Pelin Oktayoglu1, Figen Cevik, Mehmet Tahtasiz

  • 1Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dicle University, 21280 Diyarbakir, Turkey.

Case Reports in Rheumatology
|December 1, 2012
PubMed

Insights

Severe knee pain in a Behcet's disease patient was linked to bilateral bone infarction, a rare complication. Lupus anticoagulant positivity was also noted, highlighting the need for vigilance in diagnosing bone necrosis.

Area of Science:

  • Rheumatology
  • Orthopedics
  • Hematology

Background:

  • Behcet's disease (BD) is a multisystem inflammatory disorder.
  • Complications of BD include thrombosis, uveitis, and skin lesions.
  • Bone necrosis is a rare but serious complication of BD.

Purpose of the Study:

  • To report a case of bilateral knee bone infarction in a patient with Behcet's disease.
  • To highlight the association between bone infarction, Behcet's disease, and lupus anticoagulant positivity.

Main Methods:

  • Case report of a 31-year-old female patient with a 12-year history of Behcet's disease.
  • Radiologic evaluation of severe knee pain.
  • Laboratory testing for lupus anticoagulants (LA).

Main Results:

  • The patient presented with severe bilateral knee pain.
  • Radiologic evaluation revealed bone infarction in both knees.
  • Lupus anticoagulant positivity was confirmed.

Conclusions:

  • Severe joint pain without arthritis in BD patients may indicate bone necrosis.
  • Bilateral bone infarction is a rare manifestation of Behcet's disease.
  • Lupus anticoagulant positivity may be associated with bone infarction in BD.

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