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Editorial Comment to Hair follicle stem cells can be driven into a urothelial-like phenotype: an experimental study

Tokunori Yamamoto1

  • 1Department of Urology, Nagoya University Graduate School of Medicine, Nagoya, Japan. toku@med.nagoya-u.ac.jp

International Journal of Urology : Official Journal of the Japanese Urological Association
|December 4, 2012
PubMed
Abstract

No abstract available in PubMed .

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A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...

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