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The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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CMR in inflammatory vasculitis.

Subha V Raman1, Ashish Aneja, Wael N Jarjour

  • 1The Ohio State University, 473 W, 12th Ave, Suite 200, Columbus, OH 43210, USA. raman.1@osu.edu

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
|December 4, 2012
PubMed
Summary
This summary is machine-generated.

Cardiovascular magnetic resonance (CMR) aids in early diagnosis and monitoring of vasculitis (blood vessel inflammation). This imaging technique offers unique insights into both the vessel lumen and wall, improving patient care.

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Area of Science:

  • Cardiovascular Imaging
  • Rheumatology
  • Vascular Medicine

Background:

  • Vasculitis involves blood vessel inflammation, potentially causing severe organ damage.
  • Cardiovascular magnetic resonance (CMR) is increasingly used for diagnosing and monitoring vasculitis.
  • Traditional diagnostic methods can be complemented by advanced imaging techniques.

Purpose of the Study:

  • To review the utility of CMR in diagnosing and managing large- and medium-vessel vasculitides.
  • To highlight CMR's role in detecting cardiac involvement and myocardial microvascular disease in vasculitis.
  • To emphasize CMR's contribution to personalized patient care.

Main Methods:

  • Focus on case-based review of large- and medium-vessel vasculitides.
  • Inclusion of evidence on CMR for small-vessel vasculitides and myocardial microvascular disease.
  • Discussion of CMR's strengths in visualizing vessel lumen and wall.

Main Results:

  • CMR enables noninvasive visualization of vessel lumen and wall with high resolution.
  • It aids in early diagnosis, serial evaluation, and monitoring treatment response in vasculitis.
  • CMR can detect and quantify myocardial microvascular disease, crucial in small-vessel vasculitides.

Conclusions:

  • CMR is a valuable tool in the comprehensive management of vasculitis.
  • It provides critical information on vascular involvement extent and severity.
  • Future research may lead to more targeted CMR approaches for vasculitis.