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Updated: May 16, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
Published on: October 25, 2024
Rediscovering high technology from the past: thoracic surgery is back on track for multidrug-resistant tuberculosis
Emanuele Pontali1, Alberto Matteelli, Lia D'Ambrosio
1Department of Infectious Diseases, Galliera Hospital, Genoa, Italy.
Abstract:
The global emergence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB represents a core challenge for global tuberculosis control. MDR-TB and extensively drug-resistant TB are more difficult to treat and have a worse outcome compared with drug-susceptible disease. Surgery has proved to improve treatment success in MDR-TB patients. This study was designed to assess the impact of surgery in a cohort of MDR-TB patients. The authors evaluate one of the largest cohorts treated by a single center, demonstrating that specialized thoracic surgery centers may achieve excellent results with a low rate of complications after surgery, and proposing an effective model of teamwork based on pulmonologists and surgeons. A review of the evidence supporting the role of surgery in addition to chemotherapy to improve treatment outcomes in difficult-to-treat cases of TB is also performed.
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