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Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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Updated: May 16, 2026

Blood Circuit Reconstruction in an Abdominal Mouse Heart Transplantation Model

Blood Circuit Reconstruction in an Abdominal Mouse Heart Transplantation Model

Published on: June 3, 2021

[Blood transfusion during heart surgery. A retrospective nested case-control study].

J R Pérez-Valdivieso¹, P Monedero, N García-Fernández

¹Departamento de Anestesia y Reanimación, Clínica Universidad de Navarra, Universidad de Navarra, Pamplona, España. jrpvaldi@unav.es

Revista Espanola De Anestesiologia Y Reanimacion

|December 4, 2012

Summary

Intraoperative packed red blood cell transfusions in cardiac surgery patients are linked to worse outcomes. This includes higher risks of kidney damage, prolonged ventilation, and increased in-hospital mortality.

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Last Updated: May 16, 2026

Blood Circuit Reconstruction in an Abdominal Mouse Heart Transplantation Model

Blood Circuit Reconstruction in an Abdominal Mouse Heart Transplantation Model

Published on: June 3, 2021

Area of Science:

Cardiovascular Surgery
Transfusion Medicine
Critical Care Medicine

Background:

Intraoperative transfusions are common in cardiac surgery.
The association between these transfusions and patient outcomes requires further investigation.

Purpose of the Study:

To evaluate the correlation between intraoperative packed red blood cell (PRBC) transfusion and adverse outcomes in Spanish cardiac surgery patients.

Main Methods:

Retrospective, observational, multicenter study.
Analysis of 927 cardiac surgery patients from 24 Spanish hospitals (2007).
Comparison of transfused versus non-transfused patients using multivariate analyses.

Main Results:

PRBC transfusion associated with increased risk of acute kidney damage (72h post-op).
Transfused patients experienced prolonged mechanical ventilation and required hemodynamic support.
In-hospital mortality rates increased (Adjusted OR: 1.30; 95% CI: 1.19-1.42) with longer hospital stays (approx. 4 days).

Conclusions:

Intraoperative PRBC transfusion independently predicts higher risk of early acute kidney damage.
Transfusion is linked to prolonged mechanical ventilation, need for hemodynamic support, and reduced short-term survival.
Intraoperative transfusion is associated with significantly longer hospital stays.