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Updated: May 16, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Routine endoscopy to detect anastomotic leakage after esophagectomy
Richard D Page1, Atasha Asmat, James McShane
1Department of Thoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom. richard.page@lhch.nhs.uk
Early endoscopy after esophagectomy is safe and effective for diagnosing anastomotic leaks. This procedure accurately identifies gastric ischemia and leakage, guiding targeted patient care for improved healing outcomes.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Thoracic Surgery
Background:
- Anastomotic leaks are a significant complication following esophagectomy.
- Early diagnosis is crucial for effective management and improved patient outcomes.
Purpose of the Study:
- To evaluate the safety and diagnostic accuracy of endoscopy in identifying anastomotic leaks post-esophagectomy.
- To assess the utility of early endoscopic examination in managing patients after esophagectomy.
Main Methods:
- One hundred consecutive patients undergoing esophagectomy with gastric reconstruction were examined via endoscopy within the first week post-operation.
- The anastomosis and gastric mucosa were assessed for signs of ischemia, necrosis, and leakage.
Main Results:
- Endoscopy was found to be safe, causing no damage to the anastomosis or gastric conduit.
- The study identified leaks in 2 patients and ischemia in 15, with 4 showing both.
- A delayed leak was detected in one patient upon repeat endoscopy, confirming 100% accuracy in leak diagnosis.
Conclusions:
- Esophagoscopy within one week of esophagectomy is a safe and highly accurate diagnostic tool for anastomotic leaks.
- This method provides valuable information on gastric conduit status, enabling targeted patient care.
- Early endoscopic evaluation aids in managing anastomotic healing and treating leaks effectively.
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