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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
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Image domain propeller fast spin echo.

Stefan Skare1, Samantha J Holdsworth, Anders Lilja

  • 1Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Neuroradiology, Karolinska University Hospital, Stockholm, Sweden. stefan@skare.se

Magnetic Resonance Imaging
|December 4, 2012
PubMed
Summary
This summary is machine-generated.

A novel imaging technique, image domain propeller fast spin echo (iProp-FSE), offers high-resolution T2-weighted imaging. This method provides clear anatomical detail comparable to existing techniques but without motion artifacts.

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Area of Science:

  • Magnetic Resonance Imaging
  • Medical Physics
  • Radiology

Background:

  • High-resolution T2-weighted (T2-w) imaging is crucial for diagnosing various medical conditions.
  • Existing methods like PROPELLER and Cartesian FSE have limitations, including susceptibility to motion artifacts and potential for reduced image quality.

Purpose of the Study:

  • To introduce and evaluate a new pulse sequence, image domain propeller fast spin echo (iProp-FSE), for high-resolution T2-w imaging.
  • To assess the performance of iProp-FSE in terms of image quality, signal-to-noise ratio (SNR), and motion artifact reduction.

Main Methods:

  • The iProp-FSE sequence acquires data in segmented blades within the image domain, unlike k-space domain acquisition in PROPELLER.
  • Each blade uses a single-shot fast spin echo (SSFSE) with a narrow phase-encoding field of view (FOV).
  • Data from N rotated blade replicas are combined to form a full circular FOV image.

Main Results:

  • Optimal parameters for iProp-FSE include a phase FOV of 15-20%, receiver bandwidth of ±32-63 kHz, and readout time of ~300 ms, balancing SNR efficiency and T2 blurring.
  • Comparisons on axial brain data showed iProp-FSE offers comparable T2-w contrast and SNR to Cartesian FSE and PROPELLER.
  • iProp-FSE demonstrated excellent anatomical conspicuity without motion-induced artifacts like colored noise or streaks.

Conclusions:

  • iProp-FSE is a promising new pulse sequence for high-resolution T2-w MRI.
  • The sequence achieves high image quality and robustness to motion, making it suitable for clinical applications.
  • A novel slice interleaving order was proposed to enhance multislice imaging capabilities.