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Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
Published on: February 10, 2023
Identification of the MICA*070 allele by sequencing and phasing
D Moran1, S Morishima, M Malkki
1Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Human Immunology
|December 4, 2012
Abstract:
A novel MICA allele, MICA*070, was defined by sequencing. The new allele differs from the MICA*008:04 sequence in exon 2, encoding a C instead of G corresponding to cDNA nucleotide position 183. This nucleotide substitution is predicted to encode serine instead of arginine at residue 38 of the α1 domain of the MICA molecule.

