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Extracorporeal shock wave lithotripsy is effective in treating single melamine induced urolithiasis in infants and
Jianye Jia1, Xiaowei Shen, Liya Wang
1Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao tong University School of Medicine and Children's Urolithiasis Treatment Center of Chinese Ministry of Health, Shanghai, China.
Insights
Extracorporeal shock wave lithotripsy (ESWL) effectively treated melamine-induced urolithiasis in young children. This low-energy treatment showed a high stone-free rate with minimal complications, making it a preferred method.
Area of Science:
- Pediatric Urology
- Nephrolithiasis Treatment
- Shock Wave Lithotripsy
Background:
- Melamine-induced urolithiasis is a significant concern in infants and young children.
- Effective and safe treatment options for pediatric kidney stones are crucial.
Purpose of the Study:
- To evaluate the safety and efficacy of extracorporeal shock wave lithotripsy (ESWL) for single melamine-induced urolithiasis in infants and young children.
Main Methods:
- 189 infants and young children with single melamine-induced urolithiasis were treated with ESWL.
- Calculi locations included proximal ureteral, mid ureteral, distal ureteral, and kidney.
- Stone sizes ranged from 3.8 to 25 mm.
Main Results:
- A stone-free rate of 97.88% was achieved with ESWL.
- The clinically insignificant residual fragment rate was 1.59%, and the repeat treatment rate was 2.65%.
- No severe complications were observed during the mean 28-month follow-up.
Conclusions:
- Low-energy ESWL is effective in disintegrating melamine-induced calculi in pediatric patients.
- ESWL is a safe and preferred treatment for single melamine-induced urolithiasis in this age group.
Purpose:
We evaluated the safety and efficacy of extracorporeal shock wave lithotripsy in the treatment of single melamine induced urolithiasis in infants and young children.
Materials And Methods:
A total of 189 infants and young children with single melamine induced urolithiasis were referred to our center for treatment with extracorporeal shock wave lithotripsy between March 2009 and July 2010. Location of the calculus was proximal ureteral in 17 patients, mid ureteral in 5, distal ureteral in 26 and kidney in 141. Stone size ranged from 3.8 to 25 mm (mean ± SD 9.79 ± 3.83).
Results:
All patients underwent extracorporeal shock wave lithotripsy using the same device with an energy ranging from 8 to 12 kV. Stone-free rate was 97.88%, clinically insignificant residual fragment rate was 1.59% and repeat treatment rate was 2.65%. A total of 180 patients (95.24%) required only 1 lithotripsy session and 5 (2.65%) required 2 sessions. Mean ± SD number of shock waves delivered per session was 580.36 ± 190.69 (range 65 to 950). Extracorporeal shock wave lithotripsy failed to fragment stones in only 1 infant, who had a proximal ureteral stone. A total of 181 specimens were collected and analyzed by infrared spectrum, with results demonstrating that the main composition was uric acid and melamine. All patients were followed for a mean of 28 months (range 20 to 36). No severe complication, such as renal subcapsular hemorrhage, hypertension, kidney rupture or lung injury, was observed.
Conclusions:
Extracorporeal shock wave lithotripsy with low energy can effectively disintegrate melamine induced calculi. This approach has become our preferred method for treating single melamine induced urolithiasis in infants and young children.
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