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Delayed and progressive multiple suture craniosynostosis.

K Reddy1, H Hoffman, D Armstrong

  • 1Division of Neurosurgery, Hospital for Sick Children, Toronto, Ontario, Canada.

Neurosurgery
|March 1, 1990
PubMed
Summary
This summary is machine-generated.

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Progressive and delayed holocalvarial synostosis, a rare condition affecting all skull sutures, was observed in 11 patients. Surgical intervention relieved symptoms of increased intracranial pressure and developmental delay.

Area of Science:

  • Pediatric Neurosurgery
  • Craniofacial Surgery
  • Genetics

Background:

  • Craniosynostosis, the premature fusion of cranial sutures, is a common condition.
  • While single or multiple suture involvement is well-documented, progressive and delayed holocalvarial synostosis is exceptionally rare.

Observation:

  • This study reports on a cohort of 11 patients presenting with progressive and delayed holocalvarial synostosis.
  • This rare presentation involves the fusion of all calvarial sutures, occurring unusually late or progressing over time.

Findings:

  • The majority of patients exhibited clinical features indicative of raised intracranial pressure or developmental delay.
  • All 11 patients experienced symptom resolution following surgical intervention for their condition.

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Implications:

  • Highlights the diagnostic challenges and therapeutic considerations for this uncommon craniosynostosis variant.
  • Emphasizes the importance of surgical management in improving outcomes for patients with progressive and delayed holocalvarial synostosis.