Age-associated changes in muscle activity during isometric contraction
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Updated: May 16, 2026

Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations
Published on: January 25, 2018
Sridhar P Arjunan1, Dinesh K Kumar
1Biosignals Laboratory, School of Electrical and Computing Engineering, Royal Melbourne Institute of Technology University, GPO Box 2476, Melbourne, 3001, Australia. sridhar.arjunan@rmit.edu.au
Introduction:
We investigated the effect of age on the complexity of muscle activity and the variance in the force of isometric contraction.
Methods:
Surface electromyography (sEMG) from biceps brachii muscle and force of contraction were recorded from 96 subjects (20-70 years of age) during isometric contractions.
Results:
There was a reduction in the complexity of sEMG associated with aging. The relationship of age and complexity was approximated using a bilinear fit, with the average knee point at 45 years. There was an age-associated increase in the coefficient of variation (CoV) of the force of muscle contraction, and this increase was correlated with the decrease in complexity of sEMG (r(2) = 0.76).
Conclusions:
There was an age-associated increase in CoV and also a reduction in the complexity of sEMG. The correlation between these 2 factors can be explained based on the age-associated increase in motor unit density.
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