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Updated: May 16, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Pulmonary disease in small-vessel vasculitis.

Thomas R Gildea¹

¹Transplant Center, Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. gildeat@ccf.org

Cleveland Clinic Journal of Medicine

|December 4, 2012

Summary

Diagnosing small-vessel vasculitis in the lungs needs careful evaluation and imaging. Early pharmacologic treatment addresses inflammation, with procedures like dilation or surgery for airway stenosis.

Area of Science:

Pulmonology
Rheumatology
Medical Imaging

Background:

Small-vessel vasculitis (SVV) can present with diverse pulmonary manifestations.
Accurate diagnosis is challenging due to overlapping symptoms with other lung diseases.
Timely intervention is crucial for managing SVV and preventing complications.

Purpose of the Study:

To outline key diagnostic considerations for pulmonary SVV.
To emphasize the role of imaging and differential diagnosis.
To describe current treatment strategies for pulmonary SVV.

Main Methods:

Review of diagnostic criteria and imaging modalities for pulmonary SVV.
Analysis of differential diagnoses mimicking pulmonary vasculitis.
Discussion of pharmacologic and interventional treatment options.

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Main Results:

Pulmonary SVV diagnosis relies on integrated clinical, imaging, and laboratory findings.
Imaging techniques like CT angiography are vital for detecting vascular abnormalities.
Pharmacologic therapy targeting the underlying inflammation is the cornerstone of treatment.

Conclusions:

Comprehensive diagnostic approaches are essential for accurate pulmonary SVV identification.
Pharmacologic management is the primary treatment modality.
Interventional procedures may be necessary for managing secondary airway stenosis.