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Updated: May 16, 2026

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
A novel interface for hybrid mock circulations to evaluate ventricular assist devices
Gregor Ochsner1, Raffael Amacher, Alois Amstutz
1Institute for Dynamic Systems and Control, ETH Zurich, 8092 Zurich, Switzerland. gochsner@ethz.ch
Abstract:
This paper presents a novel mock circulation for the evaluation of ventricular assist devices (VADs), which is based on a hardware-in-the-loop concept. A numerical model of the human blood circulation runs in real time and computes instantaneous pressure, volume, and flow rate values. The VAD to be tested is connected to a numerical-hydraulic interface, which allows the interaction between the VAD and the numerical model of the circulation. The numerical-hydraulic interface consists of two pressure-controlled reservoirs, which apply the computed pressure values from the model to the VAD, and a flow probe to feed the resulting VAD flow rate back to the model. Experimental results are provided to show the proper interaction between a numerical model of the circulation and a mixed-flow blood pump.

