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Related Concept Videos

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform06:31

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Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay07:40

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Quantifying X-Ray Fluorescence Data Using MAPS14:58

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High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation09:17

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Suppose a car moves on flat ground and turns to the left. The centripetal force causing the car to turn in a circular path is due to friction between the tires and the road. For this, a minimum coefficient of friction is needed, or the car will move in a larger-radius curve and leave the roadway. Let's now consider banked curves, where the slope of the road helps in negotiating the curve. The greater the angle of the curve, the faster one can take the curve. It is common for race tracks for...
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Related Experiment Video

Updated: Jan 20, 2026

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
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Interventional endocardial motion estimation from electroanatomical mapping data: application to scar

Antonio R Porras1, Gemma Piella, Antonio Berruezo

  • 1Center for Computational Imaging and Simulation Technologies in Biomedicine, Universitat Pompeu Fabra, Barcelona 08018, Spain. antonio.porras@upf.edu

IEEE Transactions on Bio-Medical Engineering
|December 4, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces a new method to assess cardiac scar tissue using electroanatomical mapping and MRI data. The findings reveal that areas with low electrical voltage, indicative of scar, also exhibit reduced cardiac strain.

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Cardiac scar tissue significantly impacts heart function and is critical for planning ventricular tachycardia ablation.
  • Current methods rely on electrical voltage thresholds from electrograms to locate scar tissue during surgery.
  • Integrating cardiac mechanics could offer a more comprehensive tissue characterization.

Purpose of the Study:

  • To develop and validate a novel method for estimating endocardial motion and strain.
  • To correlate estimated cardiac mechanics with traditional scar identification methods.
  • To improve the characterization of cardiac scar tissue for ablation procedures.

Main Methods:

  • Utilized electroanatomical mapping system data and preoperative 3-D MRI-derived endocardial geometry.
  • Employed a statistical atlas constructed with bilinear models for motion estimation.
  • Validated the method with synthetic ultrasound data and applied it to ventricular tachycardia patients.

Main Results:

  • Successfully estimated endocardial motion and strain using the proposed method.
  • Demonstrated that areas with low bipolar voltage electrograms correlate with regions of low endocardial strain.
  • Provided a novel approach to characterize scar tissue beyond electrical properties.

Conclusions:

  • The developed method enables accurate estimation of endocardial motion and strain.
  • Low strain values are associated with low-voltage electrograms, suggesting a link between mechanical dysfunction and scar.
  • This approach offers potential for enhanced characterization of cardiac scar tissue in ablation planning.