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Related Experiment Video

Updated: May 16, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

A Delphi Consensus Approach to Challenging Case Scenarios in Moderate-to-Severe Psoriasis: Part 2.

Bruce E Strober1, Jennifer Clay Cather, David Cohen

  • 1Department of Dermatology, University of Connecticut School of Medicine, Farmington, CT 06032 USA.

Dermatology and Therapy
|December 4, 2012
PubMed
Summary

Expert consensus guidelines were developed using the Delphi method to aid clinicians in managing difficult-to-treat psoriasis cases, offering practical treatment options for severe and resistant psoriasis. This research addresses gaps in clinical trial data for complex patient populations.

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Last Updated: May 16, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Measuring Psoriasis Severity at Home
02:28

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Published on: March 1, 2024

Area of Science:

  • Dermatology
  • Clinical Practice Guidelines

Background:

  • Psoriasis management presents challenges for clinicians due to limited data on difficult-to-treat cases.
  • Patients with severe or refractory psoriasis are often excluded from clinical trials, necessitating expert guidance.

Purpose of the Study:

  • To develop consensus-based guidelines for managing challenging psoriasis cases.
  • To provide clinicians with evidence-informed strategies for treatment-resistant psoriasis.

Main Methods:

  • A Delphi method exercise involving a 14-expert panel was conducted.
  • The exercise included surveys and a live meeting to discuss 24 selected difficult treatment scenarios.
  • Data available as of 2009 were reviewed to establish consensus.

Main Results:

  • Five specific challenging psoriasis scenarios were presented: treatment-resistant moderate-to-severe psoriasis, palmoplantar psoriasis, erythrodermic psoriasis, pustular psoriasis, and combination therapy with methotrexate.
  • Guidelines were established for these complex cases.

Conclusions:

  • The Delphi exercise successfully generated practical guidelines for physicians managing complex psoriasis patients.
  • These guidelines aim to improve treatment outcomes for individuals with psoriasis unresponsive to standard therapies.