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Published on: December 31, 2017
Paediatric bone and joint infections are more common in boys and toddlers: a national epidemiology study
L Grammatico-Guillon1, Z Maakaroun Vermesse, S Baron
1Tours University Hospital, Tours, France. leslie.guillon@univ-tours.fr
Insights
Bone and joint infections (BJIs) in children are more common in boys and toddlers. The French National Hospital Discharge Database (HD) can track pediatric BJIs, though coding may overestimate cases.
Area of Science:
- Pediatric infectious diseases
- Epidemiology of bone and joint infections
- Healthcare database utilization
Background:
- Bone and joint infections (BJIs) in children pose a risk for growth disturbances, yet their epidemiology is poorly understood.
- Utilizing the French National Hospital Discharge Database (HD) to investigate pediatric BJIs.
Purpose of the Study:
- To examine the epidemiology of pediatric bone and joint infections (BJIs) in France.
- To assess the epidemiological and economic outcomes of childhood hematogenous BJIs.
Main Methods:
- Inclusion criteria: Children under 15 years old hospitalized with a diagnosis of BJI, sepsis, or orthopedic procedures.
- Data analysis: Descriptive analyses of epidemiological and economic outcomes for pediatric hematogenous BJIs.
- Database utilized: French National Hospital Discharge Database (HD).
Main Results:
- Overall incidence of BJIs was 22 per 100,000, with higher rates in boys (24/100,000) and toddlers.
- Septic arthritis (52%) and osteomyelitis (44%) were the most common BJIs; Staphylococcus was the most frequent pathogen (61%).
- Average hospital stay was 8.6 days, with an approximate cost of €5200 per BJI hospitalization.
Conclusions:
- The French HD database is a viable tool for studying pediatric BJIs.
- Pediatric BJIs are more prevalent in boys and toddlers.
- Potential overestimation of BJI cases due to coding of reactive arthritis as septic arthritis without bacterial confirmation.
Aim:
Little is known about bone and joint infections (BJIs) in children, despite the risk of growth disturbance. This study examined BJIs epidemiology using the French National Hospital Discharge Database (HD).
Methods:
Any child <15 years hospitalized with an HD diagnosis of BJI, alone or in combination with sepsis or orthopaedic procedure, was included. The majority of BJIs (96%) were haematogenic infections. We conducted descriptive analyses to evaluate epidemiological and economic outcomes of paediatric haematogenic BJIs.
Results:
There were 2592 paediatric patients with 2911 BJI hospitalizations and an overall incidence of 22 per 100 000. BJIs occurred more frequently in boys than girls (24 vs 19 per 100 000) and in toddlers. Septic arthritis (52%) and osteomyelitis (44%) were the most frequent infections, 16.6% of patients had a micro-organism coded (61% were Staphylococci) and 13% of had comorbidities. The mean hospital stay was 8.6 days, costing approximately €5200 per BJI stay.
Conclusion:
This national study of paediatric BJIs in France showed a higher prevalence in toddlers and boys and demonstrated that the HD database can be used to study BJIs. However, the number of BJI cases was maybe overestimated by coding reactive arthritis as septic arthritis in the absence of bacterial evidence.
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