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Updated: May 16, 2026

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
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A permuted set of a trinucleotide circular code coding the 20 amino acids in variant nuclear codes

Christian J Michel1, Giuseppe Pirillo

  • 1Equipe de Bioinformatique Théorique, BFO, LSIIT (UMR 7005), Université de Strasbourg, Pôle API, Boulevard Sébastien Brant, 67400 Illkirch, France. michel@dpt-info.u-strasbg.fr

Journal of Theoretical Biology
|December 5, 2012
PubMed
Summary

Researchers found a combinatorial link between circular codes and the genetic code. A circular code with 20 trinucleotides, enabling reading frame retrieval, corresponds to a permuted, non-circular code for 20 amino acids in variant nuclear codes.

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