Related Experiment Video
Updated: May 16, 2026

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Vaspin serum concentration in patients with type 2 diabetes and carotid plaque
1Department of Endocrinology, Fourth People's Hospital of Jinan City, Jinan, China.
Objective:
To examine whether there is an association between the serum concentration of vaspin and the presence of carotid plaque in early stage type 2 diabetes mellitus (T2DM).
Methods:
Patients (n = 61) with T2DM within 3 years of diagnosis were divided into those with and those without carotid plaque. Fasting serum vaspin levels, measured by enzymelinked immunosorbent assay, and blood pressure were compared between these two groups and also with an age-matched, apparently healthy control group (n = 26).
Results:
Fasting serum vaspin concentrations were significantly higher in patients with T2DM without carotid plaque than in controls, but significantly lower in T2DM patients with carotid plaque than in those without. Multivariate logistic regression analysis showed a significant positive association between the presence of carotid plaque and systolic blood pressure and a significant inverse association between the presence of carotid plaque and fasting serum vaspin concentration.
Conclusion:
A significant inverse association was found, in patients with T2DM within 3 years of diagnosis, between serum vaspin concentration and the presence of carotid plaque.
More Related Videos
06:04Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome
Published on: September 27, 2024
08:42A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics
Published on: September 19, 2016
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Diabetic Retinopathy
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Atherosclerosis III: Management
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Peripheral Artery Disease I: Introduction