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Related Experiment Video

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Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder

Published on: July 7, 2023

Neuromodulation in psychiatric disorders.

Yasin Temel¹, Sarah A Hescham, Ali Jahanshahi

¹Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands. y.temel@maastrichtuniversity.nl

International Review of Neurobiology

|December 5, 2012

Summary

This summary is machine-generated.

Neuromodulation offers a promising treatment for psychiatric disorders when traditional therapies fail. This review explores deep brain stimulation, vagal nerve stimulation, and transcranial stimulation for refractory symptoms.

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Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

Area of Science:

Neuroscience
Psychiatry
Medical Technology

Background:

Psychiatric disorders cause significant global disability and economic burden.
Standard treatments like medication and psychotherapy are ineffective for some patients.
Refractory psychiatric symptoms necessitate novel therapeutic approaches.

Purpose of the Study:

To review clinical data on neuromodulation techniques for major psychiatric disorders.
To discuss the neurobiological underpinnings of neuromodulation therapies.
To explore neuromodulation as an alternative for treatment-resistant patients.

Main Methods:

Review of clinical studies on neuromodulation in psychiatric disorders.
Inclusion of data from animal models to elucidate neurobiological mechanisms.
Focus on deep brain stimulation, vagal nerve stimulation, and transcranial electrical and magnetic stimulation.

Main Results:

Neuromodulation techniques show potential for managing refractory psychiatric symptoms.
Evidence supports the neurobiological basis for localized brain stimulation therapies.
Clinical data across various psychiatric disorders are synthesized.

Conclusions:

Neuromodulation presents a viable option for patients with treatment-resistant psychiatric conditions.
Understanding the neurobiology enhances the application of these advanced therapies.
Further research and clinical application of neuromodulation are warranted.