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Updated: May 16, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
A 77-year-old man with progressive dyspnea, lung fibrosis, and ossification
Luke Simon Olivera Yuhico1, Sidharth Jogani, Manju Paul
1Department of Medicine, SUNY Upstate Medical University, 142 Beresford Lane, Minoa, NY 13116, USA. yuhicol@upstate.edu
Summary:
: Diffuse pulmonary ossification is a rare clinical entity in which mature bone formation occurs within the pulmonary tissues. It has been associated with multiple pulmonary and systemic conditions and may be an indicator of disease severity and chronicity. It is often diagnosed only post mortem, because of its variable presentation with either very significant findings, mimicking other serious conditions, or very subtle onset unrecognized on imaging. In this report, we present the clinical presentation and findings in a case of diffuse pulmonary ossification diagnosed by transbronchial biopsy in a living patient.
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