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Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Published on: December 15, 2017
An advanced monitoring platform for rational design of recombinant processes
1Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 18/B, A-1190, Vienna, Austria, gerald.striedner@boku.ac.at.
Abstract:
Bioprocess engineering is an application-oriented science in an interdisciplinary environment, and a meaningful combination of different scientific disciplines is the only way to meet the challenges of bioprocess complexity. Setting up a reasoned process monitoring platform is the first step in an iterative procedure aiming at process and systems understanding, being the key to rational and innovative bioprocess design. This chapter describes a comprehensive process monitoring platform and how the resulting knowledge is translated into new strategies in process and/or host cell design.
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