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Published on: August 22, 2019
A facile no-carrier-added one pot micro-molar scale radiosynthesis of 2-[¹⁴C]-uracil
G Srinivas1, V K P Unny, K Mukkanti
1Radio Labelling Laboratory, Ogene Systems (I) Pvt. Ltd., #11-6-56, GSR Estates, Balanagar, Hyderabad 500037, Andhra Pradesh, India. srinuorg@gmail.com
Abstract:
A facile no-carrier-added one pot micro-molar scale radiolabelled synthesis of 2-[(14)C]-uracil from [(14)C]-urea and propiolic acid in the presence of polyphosphoric acid (PPA) with an yield of 48.33% and with radiochemical purity of 98% is reported in this paper.
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