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Updated: May 16, 2026

Niobium Oxide Films Deposited by Reactive Sputtering: Effect of Oxygen Flow Rate
Published on: September 28, 2019
A niobium water target for routine production of [¹⁸F]Fluoride with a MC 17 cyclotron
J Siikanen1, T Ohlsson, J Medema
1Medical Radiation Physics, Lund University Hospital, Barngatan 2:1, 221 85 Lund, Sweden. jonathan.siikanen@med.lu.se
Abstract:
A [(18)F]Fluoride water target was constructed for a Scanditronix MC 17 cyclotron, without a beam line, with a typical wide beam of ∼30 × 5 mm(2). Niobium was used as target chamber material. One hour irradiation with 45μA protons yields about 110 GBq [(18)F]Fluoride. The saturation yield is 8.0 ± 0.6 GBq/μA (EOB). The FDG yield is 60 ± 5% (EOS) with a TracerLab MX (G.E. Healthcare). More than 100 GBq FDG is routinely produced after a 2h irradiation.
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