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Related Concept Videos

Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...

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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Non syndromic oligodontia: case report.

Pradeep Tangade1, Manu Batra

  • 1Department of Public Health Dentistry, Kothiwal Dental College & Research Centre, Kanth Road, Moradabad-244001, Uttar Pradesh, India.

Ethiopian Journal of Health Sciences
|December 5, 2012
PubMed
Summary
This summary is machine-generated.

Oligodontia, a rare genetic disorder causing congenital tooth absence, is typically part of a syndrome. This case highlights a rare instance of non-syndromic oligodontia in a 13-year-old boy.

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Area of Science:

  • Dentistry
  • Genetics
  • Human Biology

Background:

  • Oligodontia is a rare genetic disorder characterized by the congenital absence of over six teeth.
  • It often presents as part of a broader genetic syndrome, with isolated occurrences being uncommon.
  • MSX1 and PAX9 genes are implicated in non-syndromic forms of oligodontia.

Purpose of the Study:

  • To report a rare case of non-syndromic oligodontia.
  • To describe the clinical presentation and examination findings in a patient with congenital tooth absence.
  • To contribute to the understanding of genetic factors in isolated oligodontia.

Main Methods:

  • Case report of a 13-year-old male patient.
  • Clinical examination to assess dental anomalies and associated physical characteristics.
  • Review of literature regarding oligodontia and its genetic basis.

Main Results:

  • The patient exhibited absence of all four second permanent molars and permanent mandibular incisors.
  • Maxillary central incisors were noted to have a conical shape.
  • Physical examination revealed no abnormalities in hair, nails, perspiration, or presence of cleft lip/palate, indicating a lack of syndromic association.

Conclusions:

  • This case represents a rare instance of non-syndromic oligodontia.
  • The findings underscore the variability in clinical presentation of oligodontia.
  • Further research into the genetic underpinnings of isolated oligodontia is warranted.