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S L Hulin-Curtis1, J L Bidwell, M J Perry

  • 1School of Veterinary Science, University of Bristol, Bristol, UK. Sarah.Curtis@bristol.ac.uk

International Journal of Immunogenetics
|December 6, 2012
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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...