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New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
[Cavernous transformation of portal vein]
Maria Inês Mascarenhas1, Marta Carneiro de Moura, Piedade Sande Lemos
1Departamento de Pediatria, Hospital Prof. Doutor Fernando Fonseca EPE, Amadora, Portugal.
Insights
Mesenteric-portal bypass (MPB) offers a therapeutic option for children with cavernous transformation of portal vein (CTPV). Early diagnosis and careful patient selection are crucial for successful MPB in pediatric CTPV cases.
Area of Science:
- Pediatric Surgery
- Vascular Surgery
- Hepatology
Background:
- Cavernous transformation of portal vein (CTPV) has limited therapeutic options in children.
- Mesenteric-portal bypass (MPB) is a viable surgical intervention for select CTPV cases.
- Pediatric CTPV often presents with complications like thrombocytopenia and splenomegaly.
Observation:
- Case 1: A 13-year-old female with CTPV diagnosed at age 7 underwent MPB.
- Case 2: A 9-year-old male with CTPV diagnosed at age 3 was deemed ineligible for MPB due to thrombosis.
- These cases highlight the importance of vascular assessment prior to MPB.
Findings:
- MPB can restore portal circulation in select pediatric CTPV patients.
- Contraindications for MPB in CTPV include pre-existing vascular thrombosis.
- Successful MPB requires careful patient selection and surgical planning.
Implications:
- MPB represents a critical treatment for pediatric CTPV when other options fail.
- Early diagnosis and vigilant monitoring are essential for identifying suitable candidates for MPB.
- Further research into optimizing MPB outcomes in pediatric CTPV is warranted.
Introduction:
In Cavernous transformation of portal vein (CTPV), therapeutic options are limited; however the restoration of circulation by mesenteric-portal bypass (MPB) is an option in selected cases. CASE REPORT 1: 13-year-old female with polymalformative syndrome. Admission at 4 months of age to Intensive Care Unit due to severe pneumonia with hemodynamic instability. Follow up due to thrombocytopenia and splenomegalia she was diagnosed CTPV at7-years old. At 13y-old she was submitted to MPB. CASE REPORT 2: 9-years-old male; severe neonatal Rh isoimmunization treated with exsanguinations. Followed-up since 6-months ofage due to thrombocytopenia and splenomegalia, and at 3 years of age he was diagnosed CTPV. Due to disease progression he was proposed as candidate to MBP which was contraindicated due to vascular thrombosis of the Rex recess.
Comments:
MBP presents as one of the few therapeutic options to CTPV in children; due to its specificity and rigid requirements it is vital the close follow up and early diagnosis.
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