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Related Experiment Videos

Effect of fibreoptic bronchoscopy on pulmonary function.

A J Peacock1, R Benson-Mitchell, R Godfrey

  • 1Southampton General Hospital.

Thorax
|January 1, 1990
PubMed
Summary

Fibreoptic bronchoscopy can impact lung function, primarily due to the topical anesthetic (lignocaine) rather than the bronchoscope itself. Patients with lung disease experience minimal additional obstruction from the bronchoscope insertion.

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Respiratory medicine·2012

Area of Science:

  • Pulmonary Medicine
  • Respiratory Physiology

Background:

  • Fibreoptic bronchoscopy is a common diagnostic procedure.
  • Deterioration in lung function post-bronchoscopy has been observed, but the causative factors remain unclear.

Purpose of the Study:

  • To investigate the specific effects of premedication, topical anesthesia, and bronchoscope insertion on lung function.
  • To differentiate the impact of each component of the bronchoscopy procedure on spirometric measurements.

Main Methods:

  • Spirometric measurements (FEV1, FVC, PEF, PIF) were assessed in patients with lung disease and healthy non-smokers.
  • Evaluated effects of premedication (papaveretum, atropine), topical lignocaine, and bronchoscope insertion sequentially.

Main Results:

  • Premedication did not significantly affect lung function.
  • Topical lignocaine caused significant decreases in FEV1, FVC, PEF, and PIF in both healthy subjects and patients.
  • Bronchoscope insertion led to further significant declines in lung function in healthy subjects, but not in patients with lung disease.

Conclusions:

  • Topical lignocaine is the primary contributor to lung function impairment after fibreoptic bronchoscopy.
  • In patients with lung disease (excluding asthma or central obstructing carcinoma), bronchoscope insertion causes minimal additional airway obstruction.

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