Related Experiment Video

Updated: Aug 18, 2026

Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa
07:27

Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa

Published on: July 12, 2018

Necrotising pneumonia and empyema due to Clostridium perfringens complicating pulmonary embolus

Y Bashir1, M K Benson

  • 1Churchill Hospital, Oxford.

Thorax
|January 1, 1990
PubMed

Insights

Necrotising pneumonia caused by Clostridium perfringens is a rare but fatal complication. This case highlights its development following pulmonary infarction, emphasizing the need for awareness.

Area of Science:

  • Pulmonary Medicine
  • Infectious Diseases
  • Bacteriology

Background:

  • Necrotising pneumonia is a severe lung infection characterized by tissue death.
  • Clostridium perfringens is an anaerobic bacterium, typically associated with gas gangrene.
  • Pulmonary infarction, the death of lung tissue due to impaired blood supply, can predispose to infections.

Observation:

  • A fatal case of necrotising pneumonia was observed.
  • The pneumonia was caused by Clostridium perfringens.
  • The condition developed as a complication following pulmonary infarction.

Findings:

  • Clostridium perfringens was identified as the causative agent of necrotising pneumonia.
  • Pulmonary infarction was the preceding condition that led to this severe pneumonia.
  • The patient experienced a fatal outcome.

Implications:

  • This case underscores the potential for Clostridium perfringens to cause severe pulmonary infections.
  • Pulmonary infarction should be recognized as a risk factor for developing necrotising pneumonia.
  • Further research into the pathogenesis and treatment of Clostridium perfringens-induced pneumonia is warranted.

More Related Videos

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

A Porcine Model of Acute Autologous Pulmonary Embolism07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...