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Published on: August 13, 2019
Effect of soy isoflavone supplementation on menopausal quality of life
Paula Amato1, Ronald L Young, Francene M Steinberg
1Oregon Health and Science University, Portland, OR 97239-4501, USA. amatop@ohsu.edu
Objective:
The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women.
Methods:
A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire.
Results:
Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups.
Conclusions:
Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.
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