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Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells
05:56

Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells

Published on: November 12, 2020

Sub-resolution lipid domains exist in the plasma membrane and regulate protein diffusion and distribution

Dylan M Owen1, David J Williamson, Astrid Magenau

  • 1Centre for Vascular Research and Australian Centre for Nanomedicine, University of New South Wales, High Street, Sydney, New South Wales 2052, Australia.

Nature Communications
|December 6, 2012
PubMed
Summary

This study provides direct evidence for distinct lipid domains in live cell membranes, showing ordered domains regulate protein behavior. These findings support a new model of plasma membrane organization.

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