Related Experiment Video
Updated: May 16, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Perforation of the mesenteric small bowel: etiologies and CT findings
John Hines1, Juliana Rosenblat, Dameon R Duncan
1Department of Radiology, Long Island Jewish Medical Center, 270-05 76th Ave, New Hyde Park, NY 11040, USA. jhines@nshs.edu
Abstract:
The purpose of this article is to illustrate and discuss the various etiologies of perforation of the mesenteric small bowel and associated findings on abdominal CT. Perforation of the mesenteric small bowel is an uncommon cause of an acute abdomen and can be due to various etiologies. In underdeveloped countries, infection is probably the most common cause, while in industrialized nations, perforation may be due to Crohn disease, diverticulitis, foreign body, trauma, tumor, mechanical obstruction, primary ischemic event, or iatrogenic causes. CT is usually the initial imaging examination in patients with an acute abdomen and is sensitive in diagnosing small bowel perforation. CT findings in the setting of small bowel perforation are often subtle, but when present, may help the radiologist determine a specific cause of perforation. The aims of this pictorial essay are to review the various causes of mesenteric small bowel perforation and to discuss and illustrate the CT findings that can help arrive at the diagnosis.
Insights
Small bowel perforation, an uncommon cause of acute abdomen, has diverse origins globally. Abdominal CT imaging is crucial for diagnosing perforation and identifying its specific cause, aiding prompt treatment.
Area of Science:
- Gastroenterology
- Radiology
- Abdominal Imaging
Background:
- Mesenteric small bowel perforation is an uncommon but serious cause of acute abdominal pain.
- Etiologies vary significantly between underdeveloped and industrialized nations.
- Computed tomography (CT) is the primary imaging modality for acute abdominal conditions.
Purpose of the Study:
- To review the diverse causes of mesenteric small bowel perforation.
- To illustrate and discuss the characteristic findings on abdominal CT scans.
- To aid radiologists in diagnosing the etiology of small bowel perforation.
Main Methods:
- Pictorial essay format.
- Review of literature on small bowel perforation etiologies.
- Illustration of CT findings associated with various causes.
Main Results:
- Infection is a common cause in underdeveloped countries.
- Industrialized nations see causes including Crohn disease, diverticulitis, foreign bodies, trauma, tumors, obstruction, ischemia, and iatrogenic factors.
- CT findings, though sometimes subtle, are key to identifying the cause of perforation.
Conclusions:
- Abdominal CT is highly sensitive for detecting small bowel perforation.
- Recognizing subtle CT findings can help differentiate between various etiologies.
- Accurate diagnosis of perforation cause via CT is essential for appropriate patient management.
Related Concept Videos
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Intestinal Obstruction II: Pathophysiology
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Diverticular Disease of the Colon
Appendicitis
