Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Morphogenesis

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.

Microbial Morphologies

Microbial Morphologies

Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...

Evolution of New Traits in Microbes

Evolution of New Traits in Microbes

Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...

Position-effect Variegation

Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Preliminary Set of Principles to Support Learning in the Context of Generative AI.

Journal of chemical education·2026

Same author

Foxi2 and Sox3 are master transcription regulators that control ectoderm germ layer specification in Xenopus.

PLoS biology·2025

Same author

Unpacking Engineering Practices for Curricular Assessment: Aligning Lab Practices and Assessment Items Using the 3D-LAP.

Journal of chemical education·2025

Same author

Investigation into the Impact of Online Learning and the Pandemic on Student Use of Mechanistic Arrows.

Journal of chemical education·2025

Same author

Foxi2 and Sox3 are master regulators controlling ectoderm germ layer specification.

bioRxiv : the preprint server for biology·2025

Same author

Examining and Supporting Mechanistic Explanations Across Chemistry and Biology Courses.

CBE life sciences education·2024

Search research articles

Related Experiment Video

Updated: May 16, 2026

Morphological Analysis of Drosophila Larval Peripheral Sensory Neuron Dendrites and Axons Using Genetic Mosaics

Morphological Analysis of Drosophila Larval Peripheral Sensory Neuron Dendrites and Axons Using Genetic Mosaics

Published on: November 7, 2011

Turning randomness into meaning at the molecular level using Muller's morphs.

Kathleen Henson¹, Melanie M Cooper, Michael W Klymkowsky

¹School of Education, University of Colorado , Boulder, CO 80309 , USA ; Present address: Miss Porter's School, 60 Main Street, Farmington, CT 06032, USA.

|December 6, 2012

Summary

Evolutionary biology education is enhanced by understanding mutation effects. A Socratic tutorial using Muller's morphs improved students' articulation of evolutionary variation.

Keywords:

Effective learning Evolution Mutation Phenotype Randomness

More Related Videos

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening

Published on: April 1, 2016

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Published on: February 16, 2017

Related Experiment Videos

Last Updated: May 16, 2026

Morphological Analysis of Drosophila Larval Peripheral Sensory Neuron Dendrites and Axons Using Genetic Mosaics

Morphological Analysis of Drosophila Larval Peripheral Sensory Neuron Dendrites and Axons Using Genetic Mosaics

Published on: November 7, 2011

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening

Published on: April 1, 2016

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Published on: February 16, 2017

Area of Science:

Evolutionary biology
Genetics
Science education

Background:

Historically, the origin of novel inheritable variations posed a challenge to evolutionary theory acceptance.
While molecular mechanisms explain variation, students struggle to connect them to evolutionary concepts.
Analysis of Biological Concept Inventory (BCI) responses showed molecular biology majors rarely use molecular ideas in evolutionary discourse.

Purpose of the Study:

To develop an educational framework for understanding evolutionary variation.
To assess the impact of a Socratic tutorial based on Muller's mutation categorization on student learning.

Main Methods:

Developed a Socratic tutorial focusing on Muller's (1932) categorization of mutation phenotypic effects.
Employed a novel vector-based method to analyze student essay responses.
Assessed changes in student thinking after a single tutorial interaction.

Main Results:

A single interaction with the Socratic tutorial significantly improved students' thinking.
Students demonstrated a clearer articulation of mutational effects post-tutorial.
Vector-based analysis revealed measurable shifts in conceptual understanding.

Conclusions:

Muller's morphs provide an effective framework for teaching mutational effects.
This approach facilitates student learning of evolutionary mechanisms.
Educational interventions can bridge the gap between molecular knowledge and evolutionary concepts.