Mindsight: diagnostics in disorders of consciousness
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Updated: May 16, 2026

SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
Published on: February 6, 2021
P Guldenmund1, J Stender, L Heine
1Coma Science group, Cyclotron Research Center and Department of Neurology, University of Liège and University Hospital of Liège, Sart-Tilman B30, 4000 Liège, Belgium.
Abstract:
Diagnosis of patients with disorders of consciousness (comprising coma, vegetative state/unresponsive wakefulness syndrome, and minimally conscious state) has long been dependent on unstandardized behavioral tests. The arrival of standardized behavioral tools, and especially the Coma Recovery Scale revised, uncovered a high rate of misdiagnosis. Ancillary techniques, such as brain imaging and electrophysiological examinations, are ever more often being deployed to aid in the search for remaining consciousness. They are used to look for brain activity patterns similar to those found in healthy controls. The development of portable and cheaper devices will make these techniques more widely available.
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