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Generalized lichen nitidus in identical twins.

Alexander K C Leung¹, Jeffrey Ng

¹Department of Pediatrics, The University of Calgary and The Alberta Children's Hospital, Calgary, AL, Canada T2M 0H5.

Case Reports in Dermatological Medicine

|December 6, 2012

Summary

This summary is machine-generated.

Generalized lichen nitidus is rare in infants. This study reports identical twins with this condition, suggesting a possible genetic link for this uncommon skin disorder.

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Area of Science:

Dermatology
Genetics

Background:

Lichen nitidus is an uncommon, idiopathic, chronic dermatosis.
It presents as minute, shiny papules, typically localized but sometimes extensive.
Infantile lichen nitidus is exceptionally rare, with only two prior reported cases.

Purpose of the Study:

To report a rare case of generalized lichen nitidus in infancy.
To explore the potential role of genetic factors in lichen nitidus.

Main Methods:

Case report of two identical twins.
Clinical observation of generalized lichen nitidus lesions.

Main Results:

Identical twins presented with generalized lichen nitidus at two months of age.
The familial occurrence in this case suggests a potential genetic predisposition.

Conclusions:

The familial occurrence of generalized lichen nitidus in identical twins supports the hypothesis that genetic factors may play a role in its development.
This case highlights the extreme rarity of infantile lichen nitidus and underscores the need for further research into its etiology.