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Updated: May 16, 2026
07:24
Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos
Published on: December 13, 2018
Laryngeal involvement of multiple myeloma
Ariel B Grobman1, Richard J Vivero, German Campuzano-Zuluaga
1Department of Otolaryngology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Suite 572, Miami, FL 33136, USA.
Case Reports in Oncological Medicine
|December 6, 2012
Summary
This study details a rare case of laryngeal multiple myeloma, a plasma cell neoplasm presenting as a de novo laryngeal mass. It reviews the pathology, epidemiology, and treatment of this uncommon condition.
Area of Science:
- Oncology
- Otolaryngology
- Hematology
Background:
- Plasma cell neoplasms, including multiple myeloma, can rarely involve the larynx.
- Extramedullary laryngeal tumors occur in 6-18% of cases, with specific sites affected with varying frequency.
Purpose of the Study:
- To discuss laryngeal multiple myeloma as a rare cause of laryngeal mass.
- To review pathologic findings, epidemiology, differential diagnosis, and treatment for laryngeal plasma cell neoplasms.
Main Methods:
- Case presentation of a 58-year-old male with IgA smoldering myeloma and laryngeal involvement.
- Literature review of plasma cell neoplasms of the larynx.
Main Results:
- Laryngeal multiple myeloma presenting as a de novo mass is extremely rare.
- The case highlights dysphonia as a symptom of laryngeal myeloma.
Conclusions:
- Laryngeal multiple myeloma is a rare entity requiring careful diagnosis and management.
- Understanding plasma cell neoplasm classification, workup, pathology, and treatment is crucial.
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