Normative growth data for the external diameters of the external and internal iliac arteries in human fetuses--an

Michał Szpinda1, Anna Szpinda

  • 1Department of Anatomy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Bydgoszcz, Poland. kizanat@cm.umk.pl

Insights

Normal growth of fetal external and internal iliac artery diameters follows quadratic functions, independent of sex. The internal iliac artery diameter is larger than the external iliac artery, with a trend towards larger right-sided vessels.

Area of Science:

  • Anatomy
  • Developmental Biology
  • Vascular Biology

Background:

  • Normative data for aorto-iliac segment diameters are crucial for diagnosing and monitoring prenatal arterial variations and pathologies.
  • Understanding normal arterial development aids in identifying congenital anomalies and planning interventions.

Purpose of the Study:

  • To establish age-specific reference intervals for external iliac artery (EIA) and internal iliac artery (IIA) diameters.
  • To generate normal growth curves for these arteries during fetal development.

Main Methods:

  • Anatomical dissection and digital-image analysis were employed.
  • The study analyzed 124 human fetuses aged 15–34 weeks.
  • External diameters of the EIA and IIA were measured.

Main Results:

  • EIA external diameters increased from 0.29–0.31 mm to 1.37–1.41 mm, following quadratic growth curves (R² = 0.82–0.86).
  • IIA external diameters ranged from 0.44 mm to 1.83–2.04 mm, also modeled by quadratic functions (R² = 0.74–0.76).
  • IIA diameters were statistically larger than EIA diameters; a trend towards larger right-sided vessels was observed, though sex differences were not significant.

Conclusions:

  • Fetal EIA and IIA external diameters are independent of sex.
  • IIA external diameter is approximately 1.5 times larger than EIA external diameter.
  • Normal growth patterns for these arterial segments are best described by quadratic functions.
Abstract