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Heart rate turbulence in mild-to-moderate aortic stenosis in boxers

A Noszczyk-Nowak1

  • 1Department of Internal Disease with Clinic of Horses, Dogs and Cats, Faculty of Veterinary Medicine, University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366 Wrocław, Poland. agnieszkann@poczta.onet.pl

Polish Journal of Veterinary Sciences
|December 11, 2012
PubMed

Insights

Heart rate turbulence (HRT) is a new parameter for predicting cardiac disease outcomes. In Boxers with subaortic stenosis (SAS), HRT values were lower, indicating compromised baroreceptor response and potential prognostic value in canine cardiology.

Area of Science:

  • Cardiology
  • Veterinary Medicine
  • Physiology

Background:

  • Heart rate turbulence (HRT) is an emerging electrocardiographic parameter in human medicine for predicting mortality in cardiac patients.
  • Limited data exists on HRT in healthy dogs and those with cardiac conditions.
  • Subaortic stenosis (SAS) is a common congenital heart defect in Boxer dogs, characterized by left ventricular outflow tract obstruction.

Purpose of the Study:

  • To compare HRT parameters between healthy Boxer dogs and those with mild to moderate SAS.
  • To investigate the relationship between HRT and echocardiographic findings in dogs with SAS.
  • To assess the prognostic potential of HRT in canine aortic stenosis.

Main Methods:

  • Electrocardiographic recordings were obtained from healthy Boxers and Boxers with varying degrees of SAS.
  • Heart rate turbulence parameters, including turbulence onset (TO) and turbulence slope (TS), were calculated.
  • Echocardiographic measurements, including left ventricular mass (LVM), were correlated with HRT values.

Main Results:

  • Dogs with SAS exhibited significantly lower values for both turbulence onset (TO) and turbulence slope (TS) compared to healthy controls.
  • Turbulence onset (TO) values showed a significant correlation with the left ventricular mass (LVM)/body mass ratio (r = 0.32; p = 0.048).
  • These findings suggest a compromised baroreceptor response in dogs with SAS.

Conclusions:

  • Heart rate turbulence is significantly altered in Boxer dogs with subaortic stenosis.
  • Reduced HRT parameters in dogs with SAS indicate impaired baroreceptor function.
  • HRT may serve as a valuable prognostic indicator for mortality risk in dogs with aortic stenosis.

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