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Friction: Problem Solving

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Friction is an essential force that influences the motion of objects in daily life. Depending on the situation, it can be either beneficial or problematic. Consider a bus with a mass of three megagrams and its center of mass at a specific point, moving along a banked road at a constant speed. The coefficient of static friction between the tires and the road is 0.5. Find the maximum angle of the banked road at which the bus would not slip or tip.
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Related Experiment Video

Updated: May 16, 2026

Measurement of Spatial Stability in Precision Grip

Measurement of Spatial Stability in Precision Grip

Published on: June 4, 2020

Fat chance! Getting a grip on a slippery modification.

Christopher T M B Tom¹, Brent R Martin

¹Program in Chemical Biology and Department of Chemistry, University of Michigan, 930 N University Avenue, Ann Arbor, Michigan 48109, United States.

ACS Chemical Biology

|December 11, 2012

Summary

Protein palmitoylation, a fatty acylation of cysteine, is vital for membrane protein function and trafficking in all eukaryotes. New chemical tools will advance the study of this dynamic post-translational modification.

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Area of Science:

Biochemistry
Molecular Biology
Cell Biology

Background:

Protein palmitoylation is a post-translational modification involving fatty acyl thioesterification of cysteine residues.
This modification is crucial for the localization, trafficking, and compartmentalization of membrane proteins.
Palmitoylation plays a dynamic role in directing signaling complexes, receptors, and channels to specific membrane compartments.

Purpose of the Study:

To summarize the current understanding of protein palmitoylation.
To highlight the pervasive role of palmitoylation across eukaryotes.
To introduce emerging chemical tools for studying palmitoylation.

Main Methods:

Chemical enrichment techniques.
Advanced mass spectrometry-based proteomics.
Analysis of protein modification dynamics.

Main Results:

Palmitoylation is a widespread modification found in animals, plants, and parasites.
The modification facilitates dynamic acylation cycles for protein trafficking.
Proteomics has identified numerous palmitoylated proteins.

Conclusions:

Protein palmitoylation is a fundamental process in eukaryotes.
Emerging chemical tools offer new possibilities for investigating palmitoylation.
Further research will elucidate the enzymes, substrates, and dynamics of this modification.