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Updated: May 16, 2026

Phagosome Migration and Velocity Measured in Live Primary Human Macrophages Infected with HIV-1
07:32

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Published on: September 5, 2016

HIV-1 Nef in macrophage-mediated disease pathogenesis

Susanna L Lamers1, Gary B Fogel, Elyse J Singer

  • 1BioInfoExperts, Thibodaux, LA, USA.

International Reviews of Immunology
|December 11, 2012
PubMed
Summary

Combined anti-retroviral therapy (cART) controls HIV-1, but the HIV-1 Nef protein in macrophages drives associated diseases like lymphoma and neurological disorders. Nef-macrophage interactions are key to understanding HIV pathogenesis.

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