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Related Experiment Video

Updated: May 16, 2026

Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis

Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis

Published on: December 18, 2019

Hereditary multiple exostoses causing cord compression.

Md Shafiqul Bari¹, M M Jahangir Alam, Fazle Rabbi Chowdhury

¹Department of Medicine, Sylhet M.A.G. Osmani Medical College, Sylhet, Bangladesh.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|December 11, 2012

Summary

This summary is machine-generated.

Hereditary multiple exostoses (HME) is a genetic disorder causing bone growths. This case highlights rare spinal cord compression in HME, successfully treated with surgery.

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Area of Science:

Genetics and Skeletal Disorders
Neurology

Background:

Hereditary multiple exostoses (HME) is an autosomal dominant skeletal disorder.
It is caused by mutations in EXT1 or EXT2 genes.
Common complications include limb deformity and growth disturbances.

Observation:

Neurological complications in HME are rare, typically due to nerve compression.
This report details a rare case of dorsal spinal cord compression in an HME patient.
The case is the first described HME presentation from Bangladesh.

Findings:

Surgical decompression was performed for the spinal cord compression.
The patient experienced improvement in myelopathy symptoms post-surgery.

Implications:

This case expands the understanding of HME's neurological manifestations.
It underscores the importance of considering spinal cord compression in HME patients with neurological deficits.
Early diagnosis and surgical intervention can improve outcomes for neurological complications in HME.