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Published on: November 6, 2019
Association of high body mass index in children with early post-tonsillectomy pain
Olubukola O Nafiu1, Amy Shanks, Samir Abdo
1Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109-0048, USA. onafiu@med.umich.edu
Insights
Children with high body mass index (BMI) experience more severe early pain after tonsillectomy. This study found a significant association between elevated BMI and increased post-tonsillectomy pain (PTP) in pediatric patients.
Area of Science:
- Pediatric Anesthesiology
- Obesity Research
- Pain Management
Background:
- Post-tonsillectomy pain (PTP) is a common complication following adenotonsillectomy (T&A).
- The relationship between pediatric body mass index (BMI) and PTP severity is not well-established.
Purpose of the Study:
- To investigate the association between high BMI in children and the occurrence and severity of early PTP.
- To test the hypothesis that high BMI correlates with increased early PTP.
Main Methods:
- Retrospective analysis of 462 children (aged 3-17) undergoing T&A.
- Patients categorized into normal or high BMI groups.
- Comparison of early PTP scores, defined as pain score ≥ 4 in the post-anesthesia care unit (PACU).
Main Results:
- 35.1% of patients were overweight or obese; 23.6% experienced moderate-severe early PTP.
- Children with high BMI showed significantly higher odds of moderate-severe early PTP (OR=7.01, p<0.001).
- High BMI emerged as a consistent risk factor for severe early PTP, even after covariate adjustment.
Conclusions:
- Elevated BMI in children is significantly associated with increased early post-tonsillectomy pain.
- Further research is warranted to elucidate the underlying mechanisms of this association.
Background:
The purpose of this investigation was to determine whether there is an association between high body mass index (BMI) in children and the occurrence of early post-tonsillectomy pain (PTP). The hypothesis tested was that high BMI is associated with increased severity of early PTP.
Methods:
We extracted data on all children aged 3-17 years that underwent adeno-tonsillectomy (T&A) over a 2-year period from our anesthesia clinical information system. Patients were classified into normal or high BMI group and early PTP scores were compared between the groups. Clinically significant (moderate-severe) early PTP was defined as pain score ≥ 4 within the first 15 min of admission to the post-anesthesia care unit (PACU).
Results:
Among 462 patients, 35.1% were overweight or obese. The overall incidence of moderate to severe early PTP was 23.6%. All the patients received at least one or more intraoperative opioid (morphine 94.2% and fentanyl 21.9%). Compared to those in the normal BMI group, children with moderate-severe PTP were older, female and more likely to be overweight or obese. Children with high BMI had significantly higher unadjusted odds of having moderate-severe early post-tonsillectomy pain (48.9% vs. 14.1%, OR=7.01, 95% CI=3.9-12.8, p<0.001). After controlling for several clinically relevant covariates, high BMI was the most consistent risk factor for moderate to severe early PTP in this cohort of children.
Conclusion:
These results indicate that high BMI in children is associated with increased early PTP. The mechanism(s) underlying this association deserve further elucidation.
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