Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 16, 2026

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

Innovative methods to assess upper limb strength and function in non-ambulant Duchenne patients.

L Servais1, N Deconinck, A Moraux

  • 1Institute of Myology, AP-HP, Groupe hospitalier La Pitié Salpétrière, Paris, France. l.servais@institut-myologie.org

Neuromuscular Disorders : NMD
|December 11, 2012
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Abstracts Association Tunisienne de Médecine Néonatale (ATMN).

La Tunisie medicale·2026
Same author

[Imaging modalities for corneal neovascularization].

Journal francais d'ophtalmologie·2026
Same author

Efficacy of progressive resistance training intensities and adequate dietary protein intake for community-dwelling frail older adults (TEAMS study), protocol for a randomised controlled trial.

BMC geriatrics·2025
Same author

[Pathophysiology and treatment of acyclovir-resistant herpes simplex virus keratitis].

Journal francais d'ophtalmologie·2025
Same author

[Viral and chlamydial conjunctivitis].

Journal francais d'ophtalmologie·2024
Same author

Early diagnosis of Duchenne muscular dystrophy - A Treat-NMD international workshop.

Neuromuscular disorders : NMD·2024

New tools accurately measure upper limb strength and function in non-ambulant individuals, particularly those with Duchenne muscular dystrophy. These reliable assessments aid in tracking disease progression and treatment effectiveness.

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Biomedical Engineering

Background:

  • Assessing upper limb function in non-ambulant patients, especially those with Duchenne muscular dystrophy (DMD), presents significant challenges.
  • Existing assessment tools may lack the precision needed to capture functional deficits in this population.

Purpose of the Study:

  • To develop and validate novel tools for precise measurement of upper limb strength and repetitive movement capacity.
  • To evaluate the feasibility and reliability of these new tools in non-ambulant individuals with DMD and healthy controls.

Main Methods:

  • Designed and implemented MyoPinch, MyoGrip, MyoWrist, and MoviPlate for assessing pinch, grip, wrist, and repetitive finger/wrist movements.
  • Assessed feasibility and reliability in 30 non-ambulant DMD patients and 30 age-matched controls.

More Related Videos

Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

An Objective and Child-friendly Assessment of Arm Function by Using a 3-D Sensor
07:25

An Objective and Child-friendly Assessment of Arm Function by Using a 3-D Sensor

Published on: February 12, 2018

Related Experiment Videos

Last Updated: May 16, 2026

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

An Objective and Child-friendly Assessment of Arm Function by Using a 3-D Sensor
07:25

An Objective and Child-friendly Assessment of Arm Function by Using a 3-D Sensor

Published on: February 12, 2018

  • Compared results with established measures like Motor Function Measure, Tapping, and Brooke Upper Extremity Functional Rating Scale.

    • Main Results:

    • MyoGrip, MyoPinch, and MoviPlate demonstrated high feasibility across tested upper limbs.
    • Excellent reliability was observed for all tests in both patient and control groups, though MyoWrist was not feasible in patients with contractures.
    • Motor capacity showed a decline correlated with time spent in a wheelchair and partially correlated with other clinical measures.

    Conclusions:

    • The validated panel of upper limb strength and function measures is suitable for Duchenne Muscular Dystrophy patients across a spectrum of weakness.
    • These tools provide a reliable and feasible method for assessing upper limb function in non-ambulant populations.
    • The findings support the use of these novel tools for monitoring disease progression and potentially evaluating interventions in DMD.