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Related Concept Videos

Overview of Protein Metabolism01:21

Overview of Protein Metabolism

Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
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Introduction to Electrolytes01:33

Introduction to Electrolytes

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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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Updated: May 16, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Nutritional rickets around the world.

Ann Prentice1

  • 1MRC Human Nutrition Research, Cambridge, United Kingdom. ann.prentice@mrc-hnr.cam.ac.uk

The Journal of Steroid Biochemistry and Molecular Biology
|December 11, 2012
PubMed
Summary

Nutritional rickets, often caused by vitamin D deficiency, causes bone deformities in children. Re-emerging in developed nations, it also presents unique challenges in Africa and Asia, requiring further study for global prevention and treatment strategies.

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Last Updated: May 16, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Area of Science:

  • Pediatrics
  • Nutritional Science
  • Public Health

Background:

  • Nutritional rickets is a significant global health issue, marked by bone deformities and often linked to vitamin D deficiency.
  • While historically reduced by public health measures, vitamin D deficiency rickets is resurging, particularly in populations with limited sun exposure.
  • In some regions like Africa and Asia, rickets occurs despite adequate sun exposure, suggesting additional etiological factors beyond vitamin D deficiency.

Purpose of the Study:

  • To summarize the current understanding of nutritional rickets, its causes, and its varied presentation globally.
  • To highlight the re-emergence of vitamin D deficiency rickets in industrialized nations and its specific risk factors.
  • To explore potential alternative causes of rickets in regions where vitamin D deficiency alone may not explain the prevalence.

Main Methods:

  • Review of existing literature on nutritional rickets.
  • Analysis of epidemiological data and clinical presentations from various global regions.
  • Examination of studies investigating etiological factors beyond vitamin D deficiency, including calcium and phosphate metabolism.

Main Results:

  • Vitamin D deficiency remains the primary cause of nutritional rickets worldwide.
  • Limited UVB exposure is a key risk factor for rickets in industrialized countries.
  • In parts of Africa and Asia, rickets in children with higher vitamin D levels suggests co-existing factors like calcium deficiency may be involved.

Conclusions:

  • Nutritional rickets requires ongoing global attention for effective prevention and treatment strategies.
  • Understanding regional variations in rickets etiology is crucial for targeted public health interventions.
  • Further research into multifactorial causes of rickets is needed to inform worldwide guidelines.